Ardem Patapoutian Արտեմ Փաթափութեան | |
|---|---|
| Kelahiran | 2 Oktober 1967 |
| Pendidikan | Universiti Amerika Beirut Universiti California, Los Angeles (BS) Institut Teknologi California (MS, PhD) |
| Anugerah | Hadiah Nobel dalam Perubatan (2021) |
| Kerjaya saintifik | |
| Bidang | Biologi molekul |
| Institusi | Scripps Research |
| Tesis | The role of the MyoD family genes during mouse development (1996) |
| Penasihat kedoktoran | Barbara Wold |
Ardem Patapoutian (Bahasa Armenia: Արտեմ Փաթափութեան; lahir 2 Oktober 1967)[1] ialah ahli biologi molekul, ahli sains saraf Amerika dan penerima Hadiah Nobel.[2] Beliau terkenal dengan karyanya dalam mencirikan reseptor PIEZO1, PIEZO2, dan TRPM8 yang mengesan tekanan, mentol, dan suhu. Patapoutian ialah profesor neurosains dan penyelidik Institut Perubatan Howard Hughes di Scripps Research di La Jolla, California. Pada tahun 2021, beliau memenangi Hadiah Nobel dalam Fisiologi atau Perubatan bersama dengan David Julius.[3]
Penerbitan terpilih
[sunting | sunting sumber]PIEZO1 + PIEZO2
[sunting | sunting sumber]- Coste, B.; Mathur, J.; Schmidt, M.; Earley, T. J.; Ranade, S.; Petrus, M. J.; Dubin, A. E.; Patapoutian, A. (September 2, 2010). "Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels". Science. American Association for the Advancement of Science (AAAS). 330 (6000): 55–60. Bibcode:2010Sci...330...55C. doi:10.1126/science.1193270. ISSN 0036-8075. PMC 3062430. PMID 20813920.
- Coste, Bertrand; Xiao, Bailong; Santos, Jose S.; Syeda, Ruhma; Grandl, Jörg; Spencer, Kathryn S.; Kim, Sung Eun; Schmidt, Manuela; Mathur, Jayanti; Dubin, Adrienne E.; Montal, Mauricio; Patapoutian, Ardem (February 19, 2012). "Piezo proteins are pore-forming subunits of mechanically activated channels". Nature. Springer Science and Business Media LLC. 483 (7388): 176–181. Bibcode:2012Natur.483..176C. doi:10.1038/nature10812. ISSN 0028-0836. PMC 3297710. PMID 22343900.
- Kim, Sung Eun; Coste, Bertrand; Chadha, Abhishek; Cook, Boaz; Patapoutian, Ardem (February 19, 2012). "The role of Drosophila Piezo in mechanical nociception". Nature. Springer Science and Business Media LLC. 483 (7388): 209–212. Bibcode:2012Natur.483..209K. doi:10.1038/nature10801. ISSN 0028-0836. PMC 3297676. PMID 22343891.
PIEZO2
[sunting | sunting sumber]- Ranade, Sanjeev S.; Woo, Seung-Hyun; Dubin, Adrienne E.; Moshourab, Rabih A.; Wetzel, Christiane; Petrus, Matt; Mathur, Jayanti; Bégay, Valérie; Coste, Bertrand; Mainquist, James; Wilson, A. J. (December 2014). "Piezo2 is the major transducer of mechanical forces for touch sensation in mice". Nature (dalam bahasa Inggeris). 516 (7529): 121–125. Bibcode:2014Natur.516..121R. doi:10.1038/nature13980. ISSN 1476-4687. PMC 4380172. PMID 25471886.
- Woo, Seung-Hyun; Ranade, Sanjeev; Weyer, Andy D.; Dubin, Adrienne E.; Baba, Yoshichika; Qiu, Zhaozhu; Petrus, Matt; Miyamoto, Takashi; Reddy, Kritika; Lumpkin, Ellen A.; Stucky, Cheryl L.; Patapoutian, Ardem (April 6, 2014). "Piezo2 is required for Merkel-cell mechanotransduction". Nature. Springer Science and Business Media LLC. 509 (7502): 622–626. Bibcode:2014Natur.509..622W. doi:10.1038/nature13251. ISSN 0028-0836. PMC 4039622. PMID 24717433.
Rujukan
[sunting | sunting sumber]- ^ Ardem Patapoutian [@ardemp] (2 October 2017). "50 years old now! @CastellanosJazz @jwNewMusic & Marshall Hawkins blew the minds of scientists et al" (Twit). Dicapai pada 5 October 2021 – melalui Twitter.
- ^ Ahlander, Johan; Burger, Ludwig (4 October 2021). "Two Americans win Medicine Nobel for work on heat and touch". Reuters (dalam bahasa Inggeris). Dicapai pada 5 October 2021.
- ^ "The Nobel Prize in Physiology or Medicine 2021". NobelPrize.org (dalam bahasa Inggeris). Diarkibkan daripada yang asal pada October 4, 2021. Dicapai pada October 4, 2021.
Pautan luar
[sunting | sunting sumber] |
Scholia mempunyai profil author tentang Ardem Patapoutian. |
- Ardem Patapoutian, PhD at Scripps Research (scripps.edu)
- The Patapoutian Lab (patapoutianlab.org)
- CV Patapoutian
- Ardem Patapoutian, PhD at Howard Hughes Medical Institute (hhmi.org)
- Ardem Patapoutian in Academic Tree (neurotree.org)
- Penerbitan Ardem Patapoutian diindekskan oleh Google Scholar
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| Pangkalan data saintifik | |
